产品货号:
Z30453
中文名称:
ZMYM2抗体
英文名称:
Anti-ZMYM2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-ZMYM2 Antibody |
| 指标别名 | ZMYM2;FIM;RAMP;ZNF198;Zinc finger MYM-type protein 2;Zinc finger protein 198 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | ZMYM2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ZMYM2 antibody was raised against a 17 amino acid peptide near the amino terminus of human ZMYM2.The immunogen is located within amino acids 120 - 170 of ZMYM2. |
| 计算分子量 | 155kDa |
| 成分 | ZMYM2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ZMYM2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression (1).The protein folding and the DNA binding ability are governed by the coordination of a zinc ion (1-3).As a member of the MYM (myeloproliferative and mental retardation) gene family,ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers,thereby enhancing the transcriptional repression of several genes (4).Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene,which may be a cause of stem cell leukemia lymphoma syndrome (SCLL) (5). |
| Uniprot ID | Q9UBW7 |
| 基因名全称 | Zinc finger,MYM-type 2 |
| 蛋白名全称 | Zinc finger,MYM-type 2 |
| 推荐稀释比 | ZMYM2 antibody can be used for detection of ZMYM2 by Western blot at 0.125 ~ 0.25μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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